A Sprained Wrist is one of the Afflictions the player can receive in The Long Dark. It can be gained in a variety of ways: Falling from a high place, moving while overburdened, or sometimes, through getting attacked by Wolves or a Bear.
A sprained wrist will not lower a player's Condition by itself, but it will prevent the player from climbing or using a weapon. However it does not affect the ability to perform other actions that require the hands.
To treat a sprained wrist, the player must either take two Painkillers or a cup of Rose Hip Tea. The condition will immediately be cured after this. Alternatively, they can rest for two hours, and the condition will be gone upon waking.